ME/CFS in the Department of Medicine

Chlamydia Pneumoniae


Charles Stratton, MD

Featured Expert: Charles W. Stratton, MD

Emerging infectious diseases are a recognized problem in clinical medicine.  Chlamydia pneumoniae was first recognized as a human pathogen in 1988. At this time, Chlamydia pneumoniae was recognized as a new cause of community-acquired respiratory tract infections. Since then, this pathogen has been associated with a number of chronic diseases, including chronic fatigue, atherosclerosis, and asthma. The pathogenesis of Chlamydia pneumoniae and its role in chronic inflammatory diseases as a cause of secondary infection that may worsen the original inflammatory process is the basis of current research interests.

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  1. Carter JD et al. Combination antibiotics as a treatment for chronic Chlamydia-induced Reactive Arthritis. (2010)
  2. Tang et al. Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls. (2009)
  3. Stratton et al. Antimicrobial treatment of multiple sclerosis. (2007)
  4. Stratton et al. Multiple sclerosis: an infectious syndrome involving Chlamydophila pneumoniae. (2006)
  5. Sriram et al. Pilot study to examine the effect of antibiotic therapy on MRI outcomes in RRMS. (2005)
  6. Mitchell et al. Chlamydia pneumoniae and acute coronary syndrome. (2005)
  7. Siwert K et al. Growth cycle-dependent pharmacodynamics of antichlamydial drugs. (2005)
  8. Sriram S et al. CNS infection with Chlamydia pneumoniae complicated by multiple strokes. (2003)
  9. Stratton CW et al. Association of Chlamydia pneumoniae with central nervous system disease. (2003)
  10. Sams HH et al. Culture and immunohistochemical evidence of Chlamydia pneumoniae in pyoderma gangrenosum. (2003)
  11. Sriram S et al. Comparative study of the presence of Chlamydia pneumoniae in cerebrospinal fluid of patients with clinical definite and monosymptomatic multiple sclerosis. (2002)
  12. King LE Jr. et al. Chlamydia pneumoniae and chronic skin infections: a focused review. (2002)
  13. King LE Jr. et al. Diabetic foot ulcers and Chlamydia pneumoniae: innocent bystander or opportunistic pathogen? (2001)
  14. Yao S et al. Regulation by beta interferon of inducible nitric oxide synthase and interleukin 12/p40 in murine macrophages exposed to Chlamydia pneumoniae antigens. (2001)
  15. Yao S et al. CSF oligoclonal bands in multiple sclerosis include antibodies against Chlamydophila. (2001)
  16. Stratton CW et al. Does Chlamydia pneumoniae play a role in the pathogenesis of multiple sclerosis? (2000)
  17. Vannucci SA et al. Pyoderma gangrenosum and Chlamydia pneumoniae infection in a diabetic man: pathogenic role or coincidence? (2000)
  18. Sriram S et al. Multiple sclerosis associated with Chlamydia pneumoniae infection of the CNS. (1998)
  19. File TM et al. The importance of Chlamydia pneumoniae as a pathogen: The 1996 Consensus Conference on Chlamydia pneumoniae Infections. (1997)


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